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Aug 11, 2019
4 min

Can a "silent" virus infection trigger MS?

Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice Steinbach, K., Vincenti, I., Egervari, K....

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Gary Birnbaum, MD

Jul 15, 2019
3 min

Making MS personal

POST-MORTEM MULTIPLE SCLEROSIS LESION PATHOLOGY IS INFLUENCED BY SINGLE NUCLEOTIDE POLYMORPHISMS Nina L. Fransen, Jakob B.A. Crusius,...

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Gary Birnbaum, MD

Jul 1, 2019
4 min

Do I really have MS?

Paper #1 - "Better explanations" in multiple sclerosis diagnostic workup: A 3-year longitudinal study. Calabrese M, Gasperini C,...

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Gary Birnbaum, MD

Jun 14, 2019
4 min

Identical but not!

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis. Nicole Y. Souren, Lisa A. Gerdes, Pavlo...

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Gary Birnbaum, MD

May 16, 2019
3 min

Inside-Out or Outside-In?

Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation. Jianqin Niu, Hui-Hsin Tsai,...

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Gary Birnbaum, MD

Apr 29, 2019
4 min

D for all MS?

The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)2D3 Induces Super-Enhancers Bound by VDR Ming Lu, Bennet J....

84 views0 comments

Gary Birnbaum, MD

Apr 11, 2019
5 min

What triggers progressive MS?

β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C,...

76 views0 comments

Gary Birnbaum, MD

Apr 11, 2019
4 min

Double Whammy!

Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis Hans Lassmann Front Immunol. 2019 Jan 10;9:3116....

37 views0 comments

Gary Birnbaum, MD

Mar 26, 2019
3 min

MRI versus AI

Automated Image Quality Evaluation of Structural Brain MRI Using an Ensemble of Deep Learning Networks Sheeba J. Sujit, PhD, Ivan...

60 views0 comments

Gary Birnbaum, MD

Mar 18, 2019
3 min

Detecting Silent MS Progression

Accuracy of Unenhanced MRI in the Detection of New Brain Lesions in Multiple Sclerosis. Eichinger P, Schön S, Pongratz V, Wiestler H,...

42 views0 comments

Gary Birnbaum, MD

Feb 24, 2019
3 min

Scaling disability

Time between expanded disability status scale (EDSS) scores. Zurawski J, Glanz BI, Chua A, Lokhande H, Rotstein D, Weiner H, Engler D,...

60 views0 comments

Gary Birnbaum, MD

Feb 17, 2019
3 min

A double-edged sword

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery. Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi...

43 views0 comments

Gary Birnbaum, MD

Feb 7, 2019
4 min

Dating Brain Cells

Dynamics of oligodendrocyte generation in multiple sclerosis Maggie S. Y. Yeung, Mehdi Djelloul, Embla Steiner, Samuel Bernard, Mehran...

24 views0 comments

Gary Birnbaum, MD

Feb 7, 2019
4 min

Tired?

Sleep Abnormalities in Multiple Sclerosis. Sakkas GK, Giannaki CD, Karatzaferi C, Manconi M Curr Treat Options Neurol. 2019 Jan...

29 views0 comments

Gary Birnbaum, MD

Jan 23, 2019
6 min

Can progressive MS be prevented?

Brown JWL, Coles A, Horakova D, Havrdova E, et al. Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary...

35 views0 comments

Dealing with MS+, and how to minimize it

Gary Birnbaum, MD

Jan 23, 2019
4 min

Dealing with MS+, and how to minimize it

Van Dyken P, Lacoste B. Impact of Metabolic Syndrome on Neuroinflammation and the Blood-Brain Barrier. Front Neurosci. 2018;12:930. Key...

39 views0 comments

Understanding ways to promote healing in MS

Gary Birnbaum, MD

Jan 23, 2019
3 min

Understanding ways to promote healing in MS

Lu G, Zhang M, Wang J, Zhang K, Wu S, Zhao X. Epigenetic regulation of myelination in health and disease. Eur J Neurosci. 2019. Key...

33 views0 comments

Gary Birnbaum, MD

Jan 23, 2019
4 min

A potential new treatment for MS

Carty M, Bowie AG. SARM: from immune regulator to cell executioner. Biochem Pharmacol. 2019. Key Points: a) Central nervous system...

41 views0 comments

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