Gary Birnbaum, MD
Hydroxychloroquine as treatment for progressive multiple sclerosis? Maybe!
Hydroxychloroquine for Primary Progressive Multiple Sclerosis Marcus W Koch, Sharanjit Kaur, Kayla Sage, Janet Kim, Myriam Levesque-Roy,...
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Gary Birnbaum, MD
- Oct 20, 2021
- 3 min
I have MS and wish to become pregnant. Now what?
Treatment of Women with Multiple Sclerosis Planning Pregnancy Krysko, K. M., Bove, R., Dobson, R., Jokubaitis, V. Hellwig, K. Curr Treat...
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Gary Birnbaum, MD
- Aug 16, 2021
- 5 min
Predicting Progression: Identifying Risks for Transition to Progressive Disease
A novel prognostic score to assess the risk of progression in relapsing−remitting multiple sclerosis patients Anna Isabella Pisani,...
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Gary Birnbaum, MD
- Apr 28, 2021
- 5 min
Aging and MS - Not easy for anyone
Multiple sclerosis and aging: comorbidity and treatment challenges Aiora Ostolaza *, Jon Corroza, Teresa Ayuso Multiple Sclerosis and...
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Gary Birnbaum, MD
- Apr 4, 2021
- 6 min
A vaccine to treat MS? Not now but ..........
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis Christina Krienke, Laura Kolb, Elif Diken et al...
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Gary Birnbaum, MD
- Jan 30, 2021
- 5 min
Oxygen for MS?
Bottom Line: Multiple sclerosis is a heterogeneous disease. It is, in my opinion, a syndrome like pneumonia, that is an illness with...
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Gary Birnbaum, MD
- Dec 29, 2020
- 6 min
A novel but possible approach for preventing COVID-19
Paper #1: De novo design of picomolar SARS-CoV-2 miniprotein inhibitors Longxing Cao, Inna Goreshnik, Brian Coventry, et al. Science 370,...
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Gary Birnbaum, MD
- Oct 29, 2020
- 5 min
One DMT may not be enough
Paper #1: Silent Progression in Disease Activity–Free Relapsing Multiple Sclerosis University of California, San Francisco MS-EPIC Team,...
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Gary Birnbaum, MD
- Aug 13, 2020
- 7 min
A most important observation!
Bottom Line: Recent work in persons with MS suggests that the gut microbiome (the population of bacteria in the gut) is altered in MS,...
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Gary Birnbaum, MD
- Jul 3, 2020
- 9 min
Yes? No? Maybe? Making treatment decisions during the coronavirus pandemic
A list of summarized articles is at the end of this posting. Bottom Line: There are at least four critical questions that persons with MS...
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Gary Birnbaum, MD
- Feb 23, 2020
- 6 min
RIS: To treat or not to treat, that is the question
Treatment Considerations in the Radiologically Isolated Syndrome. Makhani N. Curr Treat Options Neurol. 2020;22:3....
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Gary Birnbaum, MD
- Dec 19, 2019
- 5 min
Avoiding Disease Rebound
Rebound of multiple sclerosis activity after fingolimod withdrawal due to planning pregnancy: Analysis of predisposing factors. Sepulveda...
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Gary Birnbaum, MD
- Apr 29, 2019
- 4 min
D for all MS?
The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)2D3 Induces Super-Enhancers Bound by VDR Ming Lu, Bennet J....
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Gary Birnbaum, MD
- Feb 17, 2019
- 3 min
A double-edged sword
Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery. Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi...
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Gary Birnbaum, MD
- Jan 23, 2019
- 6 min
Can progressive MS be prevented?
Brown JWL, Coles A, Horakova D, Havrdova E, et al. Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary...
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Gary Birnbaum, MD
- Jan 23, 2019
- 4 min
Dealing with MS+, and how to minimize it
Van Dyken P, Lacoste B. Impact of Metabolic Syndrome on Neuroinflammation and the Blood-Brain Barrier. Front Neurosci. 2018;12:930. Key...
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Gary Birnbaum, MD
- Jan 23, 2019
- 3 min
Understanding ways to promote healing in MS
Lu G, Zhang M, Wang J, Zhang K, Wu S, Zhao X. Epigenetic regulation of myelination in health and disease. Eur J Neurosci. 2019. Key...
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Gary Birnbaum, MD
- Jan 23, 2019
- 4 min
A potential new treatment for MS
Carty M, Bowie AG. SARM: from immune regulator to cell executioner. Biochem Pharmacol. 2019. Key Points: a) Central nervous system...
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