Gary Birnbaum, MDAug 137 minA most important observation!Bottom Line: Recent work in persons with MS suggests that the gut microbiome (the population of bacteria in the gut) is altered in MS, re...
Gary Birnbaum, MDJul 39 minYes? No? Maybe? Making treatment decisions during the coronavirus pandemicA list of summarized articles is at the end of this posting. Bottom Line: There are at least four critical questions that persons with MS...
Gary Birnbaum, MDJun 45 minIs there a brain susceptibility to MS?Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS. Factor DC, Barbeau AM, Allan KC, et al. Cell. 2020;18...
Gary Birnbaum, MDMay 165 minRepairing an injured brain with goldNanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis. Rob...
Gary Birnbaum, MDApr 1610 minIs there a need for NEDA?Paper #1: Using clinically stable disease (NEDA 2) as a proxy for disease impact and employment in MS paints an incomplete picture. Roman...
Gary Birnbaum, MDFeb 236 minRIS: To treat or not to treat, that is the questionTreatment Considerations in the Radiologically Isolated Syndrome. Makhani N. Curr Treat Options Neurol. 2020;22:3. https://www.ncbi.nlm.n...
Gary Birnbaum, MDJan 2911 minA gut feeling for the brainPaper #1: An overview of the current state of evidence for the role of specific diets in multiple sclerosis. Evans E, Levasseur V, Cross ...
Gary Birnbaum, MDDec 20, 20195 minAvoiding Disease ReboundRebound of multiple sclerosis activity after fingolimod withdrawal due to planning pregnancy: Analysis of predisposing factors. Sepulveda...
Gary Birnbaum, MDOct 31, 20196 minCan pregnancy help solve some of the mysteries of MS?T Cell Repertoire Dynamics during Pregnancy in Multiple Sclerosis Ramien C, Yusko EC, Engler JB, Gamradt S, Patas K, Schweingruber N, Wil...
Gary Birnbaum, MDOct 5, 20195 minLooking backward to capture the futureSerum Neurofilament Light Chain Levels in Patients With Presymptomatic Multiple Sclerosis Kjetil Bjornevik, MD, PhD; Kassandra L. Munger,...
Gary Birnbaum, MDSep 21, 20196 minCan one predict the course of MS?Intrathecal B-cell accumulation and axonal damage distinguish MRI-based benign from aggressive onset in MS Sinah Engel,* Michaela Friedri...
Gary Birnbaum, MDAug 11, 20194 minCan a "silent" virus infection trigger MS?Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice Steinbach, K., Vincenti, I., Egervari, K. ...
Gary Birnbaum, MDJul 15, 20193 minMaking MS personalPOST-MORTEM MULTIPLE SCLEROSIS LESION PATHOLOGY IS INFLUENCED BY SINGLE NUCLEOTIDE POLYMORPHISMS Nina L. Fransen, Jakob B.A. Crusius, Joo...
Gary Birnbaum, MDJul 1, 20194 minDo I really have MS?Paper #1 - "Better explanations" in multiple sclerosis diagnostic workup: A 3-year longitudinal study. Calabrese M, Gasperini C, Tortorel...
Gary Birnbaum, MDJun 14, 20194 minIdentical but not!DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis. Nicole Y. Souren, Lisa A. Gerdes, Pavlo Lut...
Gary Birnbaum, MDMay 16, 20193 minInside-Out or Outside-In?Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation. Jianqin Niu, Hui-Hsin Tsai,...
Gary Birnbaum, MDApr 29, 20194 minD for all MS?The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)2D3 Induces Super-Enhancers Bound by VDR Ming Lu, Bennet J. McComi...
Gary Birnbaum, MDApr 11, 20195 minWhat triggers progressive MS?β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C, Watana...
Gary Birnbaum, MDApr 11, 20194 minDouble Whammy!Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis Hans Lassmann Front Immunol. 2019 Jan 10;9:3116. d...
Gary Birnbaum, MDMar 26, 20193 minMRI versus AIAutomated Image Quality Evaluation of Structural Brain MRI Using an Ensemble of Deep Learning Networks Sheeba J. Sujit, PhD, Ivan Coronad...
