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Cholesterol, Premature Aging and Progressive MS - Pathway to a New Therapy?
Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis R. B. Ionescu, A. M....
Gary Birnbaum, MD
Jan 216 min read
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Can the "revolving door" hypothesis explain MS?
Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis B. L. L. Clayton, L. Barbar, M. Sapar, K. Kalpana, C. Rao, B....
Gary Birnbaum, MD
Dec 9, 20245 min read
59 views
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Can "inverse vaccination" reverse MS, or at least halt progression?
'Inverse vaccines' could treat autoimmune disease – from multiple sclerosis to celiac disease C. Arnold Nat Med 2024 Vol. 30 Issue 5...
Gary Birnbaum, MD
Oct 30, 20245 min read
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Meaningful Magnets in MS - How New, More Powerful MRIs Are Changing Our Understanding of MS
Recent Advances in Neuroimaging of Multiple Sclerosis and Related Demyelinating Disorders Neuroimaging Clin N Am 2024 Vol. 34 Issue 3...
Gary Birnbaum, MD
Jul 21, 20246 min read
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CAR-T cells-A new treatment for MS? Or maybe not.
A CAR-T therapy for multiple sclerosis enters US trials for first time Asher Mullard Nature, 22 February 2024 https://www.ncbi.nlm.nih.go...
Gary Birnbaum, MD
Jun 13, 20247 min read
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Changing Insights Demand Change
New insights in MS challenge current concept of disease categorization
Gary Birnbaum, MD
Apr 8, 20236 min read
137 views
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Important Progress in Progressive MS
Identification of early neurodegenerative pathways in progressive multiple sclerosis M. Kaufmann, A. L. Schaupp, R. Sun, F. Coscia, C. A....
Gary Birnbaum, MD
Nov 15, 20227 min read
90 views
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Why does MS vary in severity? A very important new clue!
The Genetic Basis of Multiple Sclerosis Severity Suggests Central Nervous System Involvement A. Harroud, on behalf of the...
Gary Birnbaum, MD
May 26, 20224 min read
175 views
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Can this virus really cause MS?
Paper #1: Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis Kjetil Bjornevik,...
Gary Birnbaum, MD
Mar 18, 20227 min read
92 views
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When does MS really start?
Paper #1: Embedding electronic health records onto a knowledge network recognizes prodromal features of multiple sclerosis and predicts...
Gary Birnbaum, MD
Feb 1, 20226 min read
124 views
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Telemedicine-A Pandemic Positive
Paper #1: Providing Person-Centered Care via Telemedicine in the Era of COVID-19 in Multiple Sclerosis J. R. Abbatemarco, J. Hartman, M....
Gary Birnbaum, MD
Dec 30, 20218 min read
41 views
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Hydroxychloroquine as treatment for progressive multiple sclerosis? Maybe!
Hydroxychloroquine for Primary Progressive Multiple Sclerosis Marcus W Koch, Sharanjit Kaur, Kayla Sage, Janet Kim, Myriam Levesque-Roy,...
Gary Birnbaum, MD
Dec 3, 20215 min read
119 views
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I have MS and wish to become pregnant. Now what?
Treatment of Women with Multiple Sclerosis Planning Pregnancy Krysko, K. M., Bove, R., Dobson, R., Jokubaitis, V. Hellwig, K. Curr Treat...
Gary Birnbaum, MD
Oct 20, 20213 min read
86 views
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Predicting Progression: Identifying Risks for Transition to Progressive Disease
A novel prognostic score to assess the risk of progression in relapsing−remitting multiple sclerosis patients Anna Isabella Pisani,...
Gary Birnbaum, MD
Aug 16, 20215 min read
77 views
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A Reasonable Approach to the Treatment of MS
Improving quality, affordability, and equity of multiple sclerosis care Annette Langer-Gould, Shilpa Klocke, Brandon Beaber, Sonu M....
Gary Birnbaum, MD
Aug 7, 20216 min read
101 views
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The Challenge and Hope of Myelin Repair
Paper #1: Promoting remyelination in multiple sclerosis Nick Cunniffe and Alasdair Coles Journal of Neurology (2021) 268:30–44...
Gary Birnbaum, MD
Jul 22, 20217 min read
30 views
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Getting the skinny on MS
Paper #1: Leptin levels are associated with multiple sclerosis risk Martin Biström , Johan Hultdin , Oluf Andersen et al Multiple...
Gary Birnbaum, MD
Jun 2, 20217 min read
68 views
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Aging and MS - Not easy for anyone
Multiple sclerosis and aging: comorbidity and treatment challenges Aiora Ostolaza *, Jon Corroza, Teresa Ayuso Multiple Sclerosis and...
Gary Birnbaum, MD
Apr 28, 20215 min read
118 views
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A vaccine to treat MS? Not now but ..........
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis Christina Krienke, Laura Kolb, Elif Diken et al...
Gary Birnbaum, MD
Apr 4, 20216 min read
132 views
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Turning MS inside out!
Paper #1 - Axon-Myelin Unit Blistering as Early Event in MS Normal Appearing White Matter Antonio Luchicchi, PhD, Bert’t Hart, PhD, Irene...
Gary Birnbaum, MD
Mar 20, 20218 min read
88 views
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