Blog | Posting | Multiple Sclerosis | Updates

Cholesterol, Premature Aging and Progressive MS - Pathway to a New Therapy?

Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis R. B. Ionescu, A. M....

Gary Birnbaum, MD

Jan 216 min read

Can the "revolving door" hypothesis explain MS?

Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis B. L. L. Clayton, L. Barbar, M. Sapar, K. Kalpana, C. Rao, B....

Gary Birnbaum, MD

Dec 9, 20245 min read

Can "inverse vaccination" reverse MS, or at least halt progression?

'Inverse vaccines' could treat autoimmune disease – from multiple sclerosis to celiac disease C. Arnold Nat Med 2024 Vol. 30 Issue 5...

Gary Birnbaum, MD

Oct 30, 20245 min read

Meaningful Magnets in MS - How New, More Powerful MRIs Are Changing Our Understanding of MS

Recent Advances in Neuroimaging of Multiple Sclerosis and Related Demyelinating Disorders Neuroimaging Clin N Am 2024 Vol. 34 Issue 3...

Gary Birnbaum, MD

Jul 21, 20246 min read

CAR-T cells-A new treatment for MS? Or maybe not.

A CAR-T therapy for multiple sclerosis enters US trials for first time Asher Mullard Nature, 22 February 2024 https://www.ncbi.nlm.nih.go...

Gary Birnbaum, MD

Jun 13, 20247 min read

Changing Insights Demand Change

New insights in MS challenge current concept of disease categorization

Gary Birnbaum, MD

Apr 8, 20236 min read

Important Progress in Progressive MS

Identification of early neurodegenerative pathways in progressive multiple sclerosis M. Kaufmann, A. L. Schaupp, R. Sun, F. Coscia, C. A....

Gary Birnbaum, MD

Nov 15, 20227 min read

Why does MS vary in severity? A very important new clue!

The Genetic Basis of Multiple Sclerosis Severity Suggests Central Nervous System Involvement A. Harroud, on behalf of the...

Gary Birnbaum, MD

May 26, 20224 min read

Can this virus really cause MS?

Paper #1: Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis Kjetil Bjornevik,...

Gary Birnbaum, MD

Mar 18, 20227 min read

When does MS really start?

Paper #1: Embedding electronic health records onto a knowledge network recognizes prodromal features of multiple sclerosis and predicts...

Gary Birnbaum, MD

Feb 1, 20226 min read

Telemedicine-A Pandemic Positive

Paper #1: Providing Person-Centered Care via Telemedicine in the Era of COVID-19 in Multiple Sclerosis J. R. Abbatemarco, J. Hartman, M....

Gary Birnbaum, MD

Dec 30, 20218 min read

Hydroxychloroquine as treatment for progressive multiple sclerosis? Maybe!

Hydroxychloroquine for Primary Progressive Multiple Sclerosis Marcus W Koch, Sharanjit Kaur, Kayla Sage, Janet Kim, Myriam Levesque-Roy,...

Gary Birnbaum, MD

Dec 3, 20215 min read

I have MS and wish to become pregnant. Now what?

Treatment of Women with Multiple Sclerosis Planning Pregnancy Krysko, K. M., Bove, R., Dobson, R., Jokubaitis, V. Hellwig, K. Curr Treat...

Gary Birnbaum, MD

Oct 20, 20213 min read

Predicting Progression: Identifying Risks for Transition to Progressive Disease

A novel prognostic score to assess the risk of progression in relapsing−remitting multiple sclerosis patients Anna Isabella Pisani,...

Gary Birnbaum, MD

Aug 16, 20215 min read

A Reasonable Approach to the Treatment of MS

Improving quality, affordability, and equity of multiple sclerosis care Annette Langer-Gould, Shilpa Klocke, Brandon Beaber, Sonu M....

Gary Birnbaum, MD

Aug 7, 20216 min read

The Challenge and Hope of Myelin Repair

Paper #1: Promoting remyelination in multiple sclerosis Nick Cunniffe and Alasdair Coles Journal of Neurology (2021) 268:30–44...

Gary Birnbaum, MD

Jul 22, 20217 min read

Getting the skinny on MS

Paper #1: Leptin levels are associated with multiple sclerosis risk Martin Biström , Johan Hultdin , Oluf Andersen et al Multiple...

Gary Birnbaum, MD

Jun 2, 20217 min read

Aging and MS - Not easy for anyone

Multiple sclerosis and aging: comorbidity and treatment challenges Aiora Ostolaza *, Jon Corroza, Teresa Ayuso Multiple Sclerosis and...

Gary Birnbaum, MD

Apr 28, 20215 min read

A vaccine to treat MS? Not now but ..........

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis Christina Krienke, Laura Kolb, Elif Diken et al...

Gary Birnbaum, MD

Apr 4, 20216 min read

Turning MS inside out!

Paper #1 - Axon-Myelin Unit Blistering as Early Event in MS Normal Appearing White Matter Antonio Luchicchi, PhD, Bert’t Hart, PhD, Irene...

Gary Birnbaum, MD

Mar 20, 20218 min read