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Identical but not!
DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis. Nicole Y. Souren, Lisa A. Gerdes, Pavlo...
Gary Birnbaum, MD
Jun 14, 20194 min read
Inside-Out or Outside-In?
Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation. Jianqin Niu, Hui-Hsin Tsai,...
Gary Birnbaum, MD
May 16, 20193 min read
D for all MS?
The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)2D3 Induces Super-Enhancers Bound by VDR Ming Lu, Bennet J....
Gary Birnbaum, MD
Apr 29, 20194 min read
What triggers progressive MS?
β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C,...
Gary Birnbaum, MD
Apr 11, 20195 min read
Double Whammy!
Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis Hans Lassmann Front Immunol. 2019 Jan 10;9:3116....
Gary Birnbaum, MD
Apr 11, 20194 min read
MRI versus AI
Automated Image Quality Evaluation of Structural Brain MRI Using an Ensemble of Deep Learning Networks Sheeba J. Sujit, PhD, Ivan...
Gary Birnbaum, MD
Mar 26, 20193 min read
Detecting Silent MS Progression
Accuracy of Unenhanced MRI in the Detection of New Brain Lesions in Multiple Sclerosis. Eichinger P, Schön S, Pongratz V, Wiestler H,...
Gary Birnbaum, MD
Mar 18, 20193 min read
Scaling disability
Time between expanded disability status scale (EDSS) scores. Zurawski J, Glanz BI, Chua A, Lokhande H, Rotstein D, Weiner H, Engler D,...
Gary Birnbaum, MD
Feb 23, 20193 min read
A double-edged sword
Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery. Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi...
Gary Birnbaum, MD
Feb 17, 20193 min read
Dating Brain Cells
Dynamics of oligodendrocyte generation in multiple sclerosis Maggie S. Y. Yeung, Mehdi Djelloul, Embla Steiner, Samuel Bernard, Mehran...
Gary Birnbaum, MD
Feb 7, 20194 min read
Tired?
Sleep Abnormalities in Multiple Sclerosis. Sakkas GK, Giannaki CD, Karatzaferi C, Manconi M Curr Treat Options Neurol. 2019 Jan...
Gary Birnbaum, MD
Feb 7, 20194 min read
Can progressive MS be prevented?
Brown JWL, Coles A, Horakova D, Havrdova E, et al. Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary...
Gary Birnbaum, MD
Jan 23, 20196 min read
Dealing with MS+, and how to minimize it
Van Dyken P, Lacoste B. Impact of Metabolic Syndrome on Neuroinflammation and the Blood-Brain Barrier. Front Neurosci. 2018;12:930. Key...
Gary Birnbaum, MD
Jan 23, 20194 min read
Understanding ways to promote healing in MS
Lu G, Zhang M, Wang J, Zhang K, Wu S, Zhao X. Epigenetic regulation of myelination in health and disease. Eur J Neurosci. 2019. Key...
Gary Birnbaum, MD
Jan 23, 20193 min read
A potential new treatment for MS
Carty M, Bowie AG. SARM: from immune regulator to cell executioner. Biochem Pharmacol. 2019. Key Points: a) Central nervous system...
Gary Birnbaum, MD
Jan 23, 20194 min read
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